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Post Info TOPIC: What are the physiological functions of Neutrophil Elastase?

What are the physiological functions of Neutrophil Elastase?

Neutrophil Elastase serves several physiological functions in the body. One of its main roles is to degrade extracellular proteins, aiding in tissue remodeling and cell migration. In acute infections, Neutrophil Elastase helps to eliminate invading microorganisms by breaking down their structural proteins. Additionally, it regulates the activity of other immune cells and modulates the inflammatory response. Despite its essential functions, dysregulation of Neutrophil Elastase has been linked to various diseases, including chronic obstructive pulmonary disease (COPD), cystic fibrosis, and acute respiratory distress syndrome (ARDS). In these conditions, excessive Neutrophil Elastase activity can cause tissue damage and worsen inflammation.

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